Yes, you can.

Einhugur Plugins

There are no known limitations with Xojo Lite.

GraffitiSuite Plugins

There are no known limitations using GraffitiSuite Desktop with Xojo Lite.

Monkeybread Software Plugins

With Xojo Lite, you can use  the SQLConnectionMBS class and the SQLCommand for prepared statements and record set. In the case of using SQLDatabaseMBS or use anything with RecordSet or RowSet you need a higher level version of Xojo.

Paradigma Software Plugins

In the case of Xojo Lite and ValentinaDB ADK for Xojo, you can use the Class Methodology which does not involve the standard Xojo model for working with databases. There are no limits in working with Valentina Reports or Valentina Server.